Generic Clozaril (Clozapine)

Generic Clozaril is used for managing schizophrenia in patients who do not respond to other medicines. It is also used to decrease the risk of suicidal behavior in certain patients.

Clozapine tablet

What is this medicine?

CLOZAPINE is used to treat schizophrenia. This medicine is only used when others have not worked. It has a risk of serious side effects and is only available through a monitoring and dispensing system that includes special doctors, pharmacists, and laboratories. For the first few months of treatment, you will be required to have routine blood testing before your prescription can be refilled.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

being treated for cancer
blood disease or disorder, like leukemia
constipation, fecal impaction, or a history of an obstruction of the intestine
dementia
diabetes
heart disease
kidney disease
liver disease
low blood counts, like low white cell, platelet, or red cell counts
lung or breathing disease, like asthma
Parkinson's disease
phenylketonuria
seizures
an unusual or allergic reaction to clozapine, other medicines, foods, dyes, or preservatives
pregnant or trying to get pregnant
breast-feeding

How should I use this medicine?

Take this medicine by mouth. This medicine may be taken with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not suddenly stop taking this medicine. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.

The tablets should stay in the unopened blister package until immediately before you take your dose. If you split the tablet as part of your dose, the half-tablet that is not taken should be destroyed. Do not save this half-tablet for later use.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. If you miss your medicine for more than 2 days, you should not restart your medicine at the same dose. Contact your doctor for instructions.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

cisapride
medicines for treating cancer
mibefradil
olanzapine
phenothiazines like perphenazine, thioridazine and chlorpromazine
pimozide
ziprasidone

This medicine may also interact with the following medications:

caffeine
carbamazepine
cimetidine
ciprofloxacin
erythromycin or clarithromycin
lithium
medicines for anxiety or sleeping problems, such as diazepam or temazepam
medicines for colds, hay fever, and other allergies
medicines for high blood pressure
medicines for mental depression, anxiety, or other mood problems
nicotine
phenytoin
rifampin or rifabutin
some medicines used to treat irregular heartbeats

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Visit your doctor or health care professional for regular checks on your progress. It may be several weeks before you see the full effects of this medicine. Contact your doctor or health care professional if your symptoms get worse or if you have new symptoms.

You must have a weekly blood test when you first begin this medicine. If your blood counts stay in the right range, your tests may be reduced after 6 months to every other week. Your name will go on a national registry of patients that take this medicine, to make sure that you have never had a serious reaction to it.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

Do not treat yourself for colds, fever, diarrhea or allergies. Ask your doctor or health care professional for advice, some nonprescription medicines may increase possible side effects.

If you are going to have surgery tell your doctor or health care professional that you are taking this medicine.

If you have phenylketonuria, you should be aware that each 25 mg, orally-disintegrating tablet contains 3.1 mg of aspartame (1.74 mg of phenylalanine) and each 100 mg, orally-disintegrating tablet contains 12.4 mg of aspartame (6.96 mg of phenylalanine).

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
breathing problems
changes in vision
chest pain, fast or irregular heartbeat
confusion
difficulty sleeping, nightmares
excessive thirst and/or hunger
feeling faint or lightheaded, falls
fever, chills, sore throat, or mouth sores
muscle and joint aches and pains
nausea, vomiting, or severe loss of appetite
restlessness
seizures
stiffness, spasms, trembling
trouble passing urine or change in the amount of urine
trouble with balance, talking, walking
uncontrollable tongue or chewing movements, smacking lips or puffing cheeks
unusually weak or tired
yellowing of the eyes, skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

constipation
dry mouth
headache
increased watering of the mouth, drooling
weight gain

This list may not describe all possible side effects.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep the tablets in the packaging until the time of use. Protect from moisture. Throw away any unused medicine after the expiration date.

Buy Generic Clozaril

What is a generic medication?

Wikipedia gives the following definition:
“Generic drug (pl. generic drugs, short: generics) is a drug which is produced and distributed without a brand name. A generic must contain the same active ingredients as the original formulation. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties. By extension, therefore, generics are assumed to be identical in dose, strength, route of administration, safety, efficacy, and intended use.”

Does a generic medication differ from a brand name drug?

Not much, actually. But there is a difference, of course. To see the difference more clearly we have made a table: click here

Comparison points	Comparison	Details
Active ingredient	same	Whether a manufacturer makes brand name drugs or generic drugs, the standards are the same. The ingredients are the most important element. The ingredient in the drug that helps cure you or make you feel better, is called the "medicinal" or active ingredient. While both generic and brand name drugs must have the same amounts of good quality medicinal ingredients, other ingredients are also found in drugs.
Effect	same	Since the active ingredient is the same, the effect produced by the generic drugs and the brand name drugs is the same.
Name	different	Generic medications cannot be manufactured under brand names since this is a copyright infringement case. Generics are usually named by their active ingredient names.
Shape	different	Shape of a pills is also a copyright of a brand, thus the shape of generic pills is different from the one of the original brand
Color	different	Color of a pills is also a copyright of a brand, thus the color of generic pills is different from the one of the original brand
Price	different	Generic medications are considerably cheaper than the brand name drugs.

Why are generic pills cheaper than the brand name ones?

The principal reason for the reduced price of generic medicines is that the creation of the generic drug runs up less cost and therefore a lower price can be offered and still maintain profitability.
Manufacturers of generic drugs are mainly able to avoid the following three costs that brand name pharmaceutical companies incur: (1) costs associated with the research and development of the drug; (2) costs associated obtaining regulatory approval (i.e. proving safety and efficacy of a drug); and (3) marketing costs.
First, Generic manufacturers do not incur the cost of drug discovery and instead reverse-engineer existing brand name drugs to allow them to manufacture bioequivalent versions.
Second, generic manufacturers do not bear the burden of proving the safety and efficacy of the drugs through clinical trials - rather, generic manufacturers must prove the generic drug’s bioequivalancy to the existing drug.
Third, these companies receive the large benefit of the marketing and advertising that goes into pushing the innovator drug. The brand name drug has to prove itself in the eyes of the consumer, generic ones do not. The drugs that generic manufacturers are selling have been on the market for usually a decade or more and do not need additional advertising. For the same reason, generic manufacturers also do not give away sample doses to promote their products. The significant research, development and marketing costs incurred by the large pharmaceutical companies in introducing a new drug to the market is often cited as the reason for the high cost of new agents - they wish to recover these costs before the patent expires. Generic manufacturers do not incur these costs, with bioequivalence testing and manufacturing costing relatively little, and are able to charge significantly less than the brand.

Where are the pills you offer shipped from?

The pills we offer are produced by Indian manufacturers. To make sure our entire product list is in stock, the orders are sent out directly by our manufacturer. Usually it takes approximately two weeks for an order to be delivered to your location but in some cases may take up to three weeks.

Are your pills FDA approved?

Since the medications we offer are produced in India they are approved by the Indian FDA. Our drug manufacturers perform a series of tests, both during and after production, to show that every drug meets the requirements for that product.